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SARS 3CL Protease Antibody (PA5-143808) in IHC (P)
Immunohistochemistry analysis of SARS 3CL Protease in paraffin-embedded COVID-19 patient lung tissue. Samples were incubated in SARS 3CL Protease Polyclonal antibody (Product # PA5-143808) using a dilution of 0.5 µg/mL followed by goat anti-rabbit IgG H&L (HRP) secondary antibody at a dilution of 1:250. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 h at RT; antigen retrieval was by hea... View More
Product Details
PA5-143808
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A peptide corresponding to 16 amino acids near the amino terminus of SARS-CoV-2 (COVID-19) 3CL-Pro (NSP5) protein. The immunogen is located within the first 50 amino acids of the SARS-CoV-2 (COVID-19) 3CL-Pro (NSP5) protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3075022
Product Specific Information
Predicted reactivity based on immunogen sequence: SARS-CoV 3CL-PRO (NSP5) protein: (100%)
Target Information
Severe Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has been attributed to a novel coronavirus (SARS-CoV). The SARS 3C-like protease (SARS 3CL (pro)) is a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for corona virus replication and is considered an attractive target for therapeutics against SARS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coronavirus; COVID; COVID 19; COVID-19; SARS Coronavirus; SARS CoV; SARS CoV2; SARS-CoV-2
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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