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Immunogen sequence: HHDLDNTLNC SFLEPPSGLE QPSPSWSSRA SFSSFDTTDE GPVYCVPHEE APAESRDPEV PTVP
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 89%.
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Scavenger receptor class F member 2; scavenger receptor class F, member 1; scavenger receptor class F, member 2; scavenger receptor expressed by endothelial cells 2 (acetyl LDL receptor like); Scavenger receptor expressed by endothelial cells 2 protein; scavenger receptor type F; SREC-II; SRECRP-1
Gene Aliases: AI194363; NSR1; Scarf1; SCARF2; Scatf1; SREC-II; SREC2; SrecII; SRECRP-1; SREPCR; VDEGS; W53987; W65560
UniProt ID: (Human) Q96GP6, (Mouse) P59222
Entrez Gene ID: (Human) 91179, (Rat) 287949, (Mouse) 224024
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