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The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.
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Protein Aliases: Cancer/testis antigen 103; MGC14719; semen coagulating protein; semenoclotin; Semenogelin I; Semenogelin-1; seminal vesicle protein, secretion 1; seminal vesicle protein, secretion 2; seminal vesicle secretory protein 2; seminal vesicle secretory protein II; SGI; SgI-29; Svp-1; Svp5; SVS II; Svs5
Gene Aliases: BB115391; CT103; dJ172H20.2; RATSVPIIA; SEMG; SEMG1; SGI; Svp1; SVPIIA; Svs2; SVS2P; Svs2p2; SvsII
UniProt ID: (Human) P04279
Entrez Gene ID: (Human) 6406, (Rat) 25013, (Mouse) 53878
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