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FIGURE: 1 / 1
Sequence of this protein is as follows: MKSIILFVLS LLLILEKQAA VMGQKGGSKG QLPSGSSQFP HGKKGQHYFG QKDQQHTKSK GSFSIQHTYH VDINDHDWTR KSQQYDLNAL HKATKSKQHL GGSQQLLNYK QEGRDHDKSK GHFHMIVIHH KGGQAHHGTQ NPSQDQGNSP SGKGLSSQCS NTEKRLWVHG LSKEQASASG AQKGRTQGGS QSSYVLQTEE LVVNKQQRET KNSHQNKGHY QNVVDVREEH SSKLQTSLHP AHQDRLQHGP KDIFTTQDEL LVYNKNQHQT KNLNQDQEHG RKAHKISYPS SRTEERQLHH GEKSVQKDVS KGSISIQTEE KIHGKSQNQV TIHSQDQEHG HKENKISYQS SSTEERHLNC GEKGIQKGVS KGSISIQTEE QIHGKSQNQV RIPSQAQEYG HKENKISYQS SSTEERRLNS GEKDVQKGVS KGSISIQTEE KIHGKSQNQV TIPSQDQEHG HKENKMSYQS SSTEERRLNY GGKSTQKDVS QSSISFQIEK LVEGKSQIQT PNPNQDQWSG QNAKGKSGQS ADSKQDLLSH EQKGRYKQES SESHNIVITE HEVAQDDHLT QQYNEDRNPI ST
The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20.
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Protein Aliases: Semenogelin 2; Semenogelin II; Semenogelin-2; SGII
Gene Aliases: SEMG2; SGII
UniProt ID: (Human) Q02383
Entrez Gene ID: (Human) 6407
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