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SESN2 Antibody (A305-881A) in WB
Detection of human SESN2 by western blot. Samples: Whole cell lysate (50 µg) from HEK293T, RKO, and K-562 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SESN2 antibody (A305-881A lot 1) used for WB at 0.04 mg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A305-881A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A region between residue 275 and 325 of human Sestrin-2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate, tris citrate
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Predicted reactivity by homology: Orangutan, Mouse.
Target Information
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; Sestrin-2
Gene Aliases: HI95; SES2; SESN2; SEST2
UniProt ID: (Human) P58004
Entrez Gene ID: (Human) 83667
regulation of protein phosphorylation
fatty acid beta-oxidation
autophagy
response to glucose
positive regulation of macroautophagy
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
mitochondrial DNA metabolic process
response to insulin
cellular response to oxidative stress
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
protein kinase B signaling
glucose import
triglyceride homeostasis
cellular response to amino acid stimulus
cellular response to leucine
reactive oxygen species metabolic process
regulation of gluconeogenesis involved in cellular glucose homeostasis
cellular oxidant detoxification
positive regulation of protein localization to nucleus
regulation of response to reactive oxygen species
negative regulation of translation in response to endoplasmic reticulum stress
negative regulation of TORC1 signaling
regulation of cAMP-dependent protein kinase activity
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