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Product Details
PA5-96532
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human SET/TAF1 (NP_0030022)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808334
Product Specific Information
Immunogen sequence: MSAPAAKVSK KELNSNHDGA DETSEKEQQE AIEHIDEVQN EIDRLNEQAS EEILKVEQKY NKLRQPFFQK RSELIAKIPN FWVTTFVNHP QVSALLGEED EEALHYLTRV EVTEFEDIKS GYRIDFYFDE NPYFENKVLS KEFHLNESGD PSSKSTEIKW KSGKDLTKRS SQTQNKASRK RQHEEPESFF TWFTDHSDAG ADELGEVIKD DIWPNPLQYY LVPDMDDEEG EGEEDDDDDE EEEGLEDIDE EGDEDEGEED EDDDEGEEGE EDEGEDD; Positive Samples: 293T, MCF7, HeLa; Cellular Location: Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol, nucleoplasm
Target Information
SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HLA-DR-associated protein II; I IGAAD; I-2PP2A; IGAAD; Inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; Liver regeneration-related protein LRRGR00002; OTTHUMP00000022286; PHAPII; Phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor; Protein SET; RP11-216B9.3; SET nuclear oncogene; SET translocation; SET translocation (myeloid leukemia-associated); TAF-1a; TAF-1b; TAF-I; Template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor
Gene Aliases: 2610030F17Rik; 2PP2A; 5730420M11Rik; AA407739; Ab1-115; I-2PP2A; I2PP2A; IGAAD; IPP2A2; PHAPII; SET; StF-IT-1; TAF-I; TAF-IBETA
UniProt ID: (Human) Q01105, (Mouse) Q9EQU5, (Rat) Q63945
Entrez Gene ID: (Human) 6418, (Mouse) 56086, (Rat) 307947
DNA replication
nucleosome assembly
nucleosome disassembly
nucleocytoplasmic transport
viral process
regulation of protein phosphatase type 2A activity
negative regulation of histone acetylation
negative regulation of catalytic activity
regulation of mRNA stability
negative regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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