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Product Details
6418-MSM1-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PCRP-SET-1C6
Immunogen
Recombinant full-length human SET protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HLA-DR-associated protein II; I IGAAD; I-2PP2A; IGAAD; Inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; OTTHUMP00000022286; PHAPII; Phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor; Protein SET; RP11-216B9.3; SET nuclear oncogene; SET translocation (myeloid leukemia-associated); TAF-1a; TAF-1b; TAF-I; Template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor
Gene Aliases: 2PP2A; I2PP2A; IGAAD; IPP2A2; PHAPII; SET; TAF-I; TAF-IBETA
UniProt ID: (Human) Q01105
Entrez Gene ID: (Human) 6418
DNA replication
nucleosome assembly
nucleosome disassembly
nucleocytoplasmic transport
viral process
regulation of protein phosphatase type 2A activity
negative regulation of histone acetylation
negative regulation of catalytic activity
regulation of mRNA stability
negative regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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