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Product Details
66293-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H6E5
Immunogen
SETDB1 Fusion Protein Ag21644 (1-350 aa encoded by BC009362)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSSLPGCIG LDAATATVES EEIAELQQAV VEELGISMEE LRHFIDEELE KMDCVQQRKK QLAELETWVI QKESEVAHVD QLFDDASRAV TNCESLVKDF YSKLGLQYRD SSSEDESSRP TEIIEIPDED DDVLSIDSGD AGSRTPKDQK LREAMAALRK SAQDVQKFMD AVNKKSSSQD LHKGTLSQMS GELSKDGDLI VSMRILGKKR TKTWHKGTLI AIQTVGPGKK YKVKFDNKGK SLLSGNHIAY DYHPPADKLY VGSRVVAKYK DGNQVWLYAG IVAETPNVKN KLRFLIFFDD GYASYVTQSE LYPICRPLKK TWEDIEDISC RDFIEEYVTA YPNRPMVLLK S (1-350 aa encoded by BC009362)
Target Information
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ERG-associated protein with a SET domain, ESET; ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; Histone H3-K9 methyltransferase 4; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SET domain ERG-associated histone methyltransferase; SET domain, bifurcated 1; tudor domain containing 21
Gene Aliases: AU022152; ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; mKIAA0067; SETDB1; TDRD21
UniProt ID: (Human) Q15047
Entrez Gene ID: (Human) 9869, (Mouse) 84505, (Rat) 689883
transcription, DNA-templated
Ras protein signal transduction
response to vitamin
histone lysine methylation
response to ethanol
positive regulation of methylation-dependent chromatin silencing
negative regulation of transcription from RNA polymerase II promoter
inner cell mass cell proliferation
regulation of transcription, DNA-templated
chromatin modification
methylation
histone H3-K9 trimethylation
bone development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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