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SETDB2 Antibody (PA5-110357) in WB
Western blot analysis of SETDB2 in extracts of various cell lines. Samples were incubated with SETDB2 Polyclonal antibody (Product # PA5-110357) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-110357
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 148-378 of human SETDB2 (NP_1141212)
Conjugate
Form
Liquid
Concentration
1.04 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855768
Product Specific Information
Immunogen sequence: SGACLMKMPL NLKGENPLQL PIKCHFQRRH AKTNSHSSAL HVSYKTPCGR SLRNVEEVFR YLLETECNFL FTDNFSFNTY VQLARNYPKQ KEVVSDVDIS NGVESVPISF CNEIDSRKLP QFKYRKTVWP RAYNLTNFSS MFTDSCDCSE GCIDITKCAC LQLTARNAKT SPLSSDKITT GYKYKRLQRQ IPTGIYECSL LCKCNRQLCQ NRVVQHGPQV RLQVFKTEQK G
Target Information
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bifurcated 2; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; histone-lysine N-methyltransferase SETDB2; SET domain; Setdb2-Phf11-1-Phf11-2 fusion
Gene Aliases: Clld8; Gm293; KMT1F
Entrez Gene ID: (Mouse) 239122
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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