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SEZ6L Antibody (PA5-143994) in ICC/IF
Immunocytochemistry analysis of SEZ6L in U2OS cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in SEZ6L Polyclonal antibody (Product # PA5-143994) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Rabbit IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate f... View More
Product Details
PA5-143994
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human SEZ6L recombinant protein (Position: E662-E953).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3075208
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Target Information
SEZ6L (seizure related 6 homolog-like) is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acupuncture induced gene 1; Acupuncture-induced protein 1-L; Brain-specific receptor-like protein B; BSRP-B; Seizure 6-like protein; seizure related 6 homolog (mouse)-like; seizure related gene 6-like
Gene Aliases: Acig1; AI843918; AIG1; Aig1l; AW539724; BSRP-B; KIAA0927; mKIAA0927; RGD1563628; SEZ6L; UNQ2542/PRO6094
UniProt ID: (Human) Q9BYH1, (Mouse) Q6P1D5
Entrez Gene ID: (Human) 23544, (Mouse) 56747, (Rat) 304554
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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