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FIGURE: 1 / 2
Predicted reactivity by homology: Bovine.
SF3B5 is a protein coding gene involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.
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Protein Aliases: MGC3133; Pre-mRNA-splicing factor SF3b 10 kDa subunit; SF3b5; Splicing factor 3B subunit 5; splicing factor 3b, subunit 5, 10kDa
Gene Aliases: 10kDa; 1110005L13Rik; AU043053; SF3B10; SF3B5; Ysf3
UniProt ID: (Human) Q9BWJ5, (Mouse) Q923D4
Entrez Gene ID: (Human) 83443, (Mouse) 66125
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