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Immunogen sequence: DFWCDVVIAD LHPVGWCTQN NKVLMPPDAI KEKYTDWTEF LIRDLTGSRT APANLLEGPL RGKGPIDLIT VGSLIELQDS QN
The SFMBT2 (Scm-like with four MBT domains 2) gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Sfmbt2 is a Polycomb group (PcG) gene that maps to the proximal region of Chromosome 2, and is a putative imprinted gene. Sfmbt2 is the first imprinted gene within this region to be identified. Studies indicate that six different translocations involving proximal chromosome 2 results in lethality when present as a maternal uniparental duplication.
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Protein Aliases: Scm-like with 4 MBT domains protein 2; Scm-like with four MBT domains protein 2; Scm-related gene containing four mbt domains 2
Gene Aliases: KIAA1617; SFMBT2
UniProt ID: (Human) Q5VUG0
Entrez Gene ID: (Human) 57713
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