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This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.
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Protein Aliases: 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; collectin 5; Collectin-5; PSP-A; Pulmonary surfactant-associated protein A2; SP-2A beta; SP-2A gamma; SP-A2; SP-A2 alpha; SP-A2 delta; SPA2; Surfactant Protein A2; surfactant, pulmonary-associated protein A2A
Gene Aliases: COLEC5; PSAP; PSP-A; PSPA; SFTP1; SFTPA; SFTPA2; SFTPA2B; SP-2A; SP-A; SPA2; SPAII
UniProt ID: (Human) Q8IWL1
Entrez Gene ID: (Human) 729238
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