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FIGURE: 1 / 1
SFTPD Antibody (MA5-51444) in WB
Western blot analysis of SFTPD in various lysates. Samples were incubated with SFTPD Recombinant monoclonal antibody (Product # MA5-51444) using a dilution of 1:70,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
MA5-51444
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1X4V10
Immunogen
A synthesized peptide derived from human Surfactant protein D/SP-D.
Conjugate
Form
Liquid
Concentration
0.75 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_3093898
Product Specific Information
Immunogen sequence: MLLFLLSALV LLTQPLGYLE AEMKTYSHRT MPSACTLVMC SSVESGLPGR DGRDGREGPR GEKGDPGLPG AAGQAGMPGQ AGPVGPKGDN GSVGEPGPKG DTGPSGPPGP PGVPGPAGRE GPLGKQGNIG PQGKPGPKGE AGPKGEVGAP GMQGSAGARG LAGPKGERGV PGERGVPGNT GAAGSAGAMG PQGSPGARGP PGLKGDKGIP GDKGAKGESG LPDVASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF
Target Information
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collectin7; CP4; Lung surfactant protein D; PSP-D; PSP-D Surfactant protein D; Pulmonary surfactant associated protein PSP-D; pulmonary surfactant protein D; Pulmonary surfactant-associated protein D; SFTP 4; surfactant associated protein D; Surfactant associated protein pulmonary 4; surfactant, pulmonary-associated protein D
Gene Aliases: AI573415; Sftp4; Sftpd; SP-D; SPD
UniProt ID: (Rat) P35248, (Mouse) P50404
Entrez Gene ID: (Rat) 25350, (Mouse) 20390
respiratory gaseous exchange
opsonization
response to corticosteroid
negative regulation of interleukin-2 production
negative regulation of T cell proliferation
surfactant homeostasis
innate immune response
lung alveolus development
negative regulation of phagocytosis
positive regulation of phagocytosis
regulation of liquid surface tension
response to glucocorticoid
response to hyperoxia
response to growth factor
immune system process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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