Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: AGMKTYSHRT MPSACTLVMC SSVESGLPGR DGRDGREGPR GEKGDPGLPG AAGQAGMPGQ AGPVGPKGDN GSVGEPGPKG DTGPSGPPGP PGVPGPAGRE GPLGKQGNIG PQGKPGPKGE AGPKGEVGAP GMQGSAGARG LAGPKGERGV PGERGVPGNT GAAGSAGAMG PQGSPGARGP PGLKGDKGIP GDKGAKGESG LPDVASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG KPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collectin-7; Collectin7; Lung surfactant protein D; PSP-D; PSP-D Surfactant protein D; pulmonary surfactant apoprotein; Pulmonary surfactant associated protein PSP-D; Pulmonary surfactant-associated protein D; SFTP 4; Surfactant associated protein pulmonary 4; surfactant-associated protein, pulmonary 4
Gene Aliases: COLEC7; PSP-D; PSPD; SFTP4; SFTPD; SP-D
UniProt ID: (Human) P35247
Entrez Gene ID: (Human) 6441
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