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Product Details
12407-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SGCE Fusion Protein Ag3118 (1-300 aa encoded by BC021709)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQLPRWWEL GDPCAWTGQG RGTRRMSPAT TGTFLLTVYS IFSKVHSDRS VYPSAGVLFV HVLEREYFKG EFPPYPKPGE ISNDPITFNT NLMGYPDRPG WLRYIQRTPY SDGVLYGSPT AENVGKPTII EITAYNRRTF ETARHNLIIN IMSAEDFPLP YQAEFFIKNM NVEEMLASEV LGDFLGAVKN VWQPERLNAI NITSALDRGG RVPLPINDLK EGVYVMVGAD VPFSSCLREV ENPQNQLRCS QEMEPVITCD KKFRTQFYID WCKISLVDKT KQVSTYQEVI RGEGILPDGG E (1-300 aa encoded by BC021709)
Target Information
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dystonia 11, myoclonic; Epsilon sarcoglycan; Epsilon SG; Epsilon-sarcoglycan; epsilon-sarcoglycan {ECO:0000312|EMBL:AAO37579.1}; Epsilon-SG; epsilon-SG {ECO:0000250|UniProtKB:O43556}; sarcoglycan; sarcoglycan, epsilon; sgce {ECO:0000312|EMBL:AAO37579.1, ECO:0000312|RGD:1303201}
Gene Aliases: DYT11; e-SG; ESG; SGCE; UNQ433/PRO840
UniProt ID: (Human) O43556, (Mouse) O70258, (Rat) Q6YAT4
Entrez Gene ID: (Human) 8910, (Mouse) 20392, (Rat) 432360
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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