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FIGURE: 1 / 3
Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (94%), Pig (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dystonia 11, myoclonic; Epsilon sarcoglycan; Epsilon SG; Epsilon-sarcoglycan; Epsilon-SG; sarcoglycan; sarcoglycan, epsilon
Gene Aliases: DYT11; e-SG; ESG; SGCE; UNQ433/PRO840
UniProt ID: (Human) O43556, (Mouse) O70258
Entrez Gene ID: (Human) 8910, (Mouse) 20392
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