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Product Details
12493-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SGEF Fusion Protein Ag3198 (1-301 aa encoded by BC016628)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MISFLILPM QRVTRLPLLM DTICQKTPKD SPKYEVCKRA LKEVSKLVRL CNEGARKMER TEMMYTINSQ LEFKIKPFPL VSSSRWLVKR GELTAYVEDT VLFSRRTSKQ QVYFFLFKDV LIITKKKSEE SYNVNDYSLR DQLLVESCDN EELNSSPGKN SSTMLYSRQS SASHLFTLTV LSNHANEKVE MLLGAETQSE RARWITALGH SSGKPPADRT SLTQVEIVRS FTAKQPDELS LQVADVVLIY QRVSDGWYEG ERLRDGERGW FPMECAKEIT CQATIDKNVE RMGRLLGLET NV (1-301 aa encoded by BC016628)
Target Information
Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Rho guanine nucleotide exchange factor (GEF) 26; Rho guanine nucleotide exchange factor 26; SH3 domain-containing guanine exchange factor; Src homology 3 domain-containing guanine nucleotide exchange factor; testicular tissue protein Li 171
Gene Aliases: ARHGEF26; CSGEF; HMFN1864; SGEF
UniProt ID: (Human) Q96DR7
Entrez Gene ID: (Human) 26084
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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