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Product Details
PA5-52824
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SGK2
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647215
Product Specific Information
Immunogen sequence: EVLRKEPYDR AVDWWCLGAV LYEMLHGLPP FYSQDVSQMY ENILHQPLQI PGGRTVAACD LLQSLLHKDQ RQRLGSKADF LEIKNHVFFS PINWDDLYHK RLTPPFNPNV TGPADLKHFD PEFTQEAVSK SIGCTPD
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Target Information
SGK2 is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Although little is known about the transcriptional regulation of SGK2, the protein has been shown to be phosphorylated and activated by 3 phosphoinositide dependent protein kinase 1 (PDK1), and to a lesser extent insulin like growth factor 1, in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; Serum/glucocorticoid-regulated kinase 2
Gene Aliases: AI098171; AW146006; dJ138B7.2; H-SGK2; SGK2; Sgkl
UniProt ID: (Human) Q9HBY8, (Rat) Q8R4U9, (Mouse) Q9QZS5
Entrez Gene ID: (Human) 10110, (Rat) 171497, (Mouse) 27219
protein serine/threonine kinase activity
calcium channel regulator activity
ATP binding
potassium channel regulator activity
sodium channel regulator activity
chloride channel regulator activity
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein modifying enzyme
regulation of cell growth
protein phosphorylation
cellular sodium ion homeostasis
response to oxidative stress
positive regulation of sodium ion transport
peptidyl-serine phosphorylation
positive regulation of transporter activity
ion transmembrane transport
intracellular signal transduction
regulation of cell proliferation
regulation of apoptotic process
phosphorylation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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