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Invitrogen
SGMS2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
SGMS2 Antibody (PA5-82521)
Relative expression in different tissues in IHC: Detection of differential expression levels of SGMS2 demonstrates antibody specificity. Immunohistochemical analysis of SGMS2 using anti-SGMS2 Polyclonal Antibody (Product #PA5-82521), shows significant staining of SGMS2 in gallbladder and shows minimal or weak staining in lymph node tissues. The relative expression levels of SGMS2 within each tissue is show... View More
Product Details
PA5-82521
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SGMS2. Recombinant protein control fragment (Product #RP-91268).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789679
Product Specific Information
Immunogen sequence: IIETAKLEEH LENQPSDPTN TYARPAEPVE EENKNGNGKP KSLSSGLRKG TKKYPDYIQI AMPTESR
Target Information
A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC26963; Phosphatidylcholine:ceramide cholinephosphotransferase 2; SM synthase; Sphingomyelin synthase 2
Gene Aliases: SGMS2; SMS2
UniProt ID: (Human) Q8NHU3
Entrez Gene ID: (Human) 166929
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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