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Invitrogen
SGSH Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
SGSH Antibody (PA5-82831)
Relative expression in different tissues in IHC: Detection of differential expression levels of SGSH demonstrates antibody specificity. Immunohistochemical analysis of SGSH using anti-SGSH Polyclonal Antibody (Product #PA5-82831), shows significant staining of SGSH in adrenal gland and shows minimal or weak staining in skeletal muscle tissues. The relative expression levels of SGSH within each tissue is sh... View More
Product Details
PA5-82831
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SGSH. Recombinant protein control fragment (Product #RP-93497).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789987
Product Specific Information
Immunogen sequence: CEKFGNGESG MGRIPDWTPQ AYDPLDVLVP YFVPNTPAAR ADLAAQYTTV GRMDQGVGLV LQELRDAGVL NDTLVIFTSD NGIPFPSGRT NLYWPGTAEP L
Target Information
SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: heparan sulfate sulfatase; mucopolysaccharidosis type IIIA; N-sulphoglucosamine sulphohydrolase; Sulfoglucosamine sulfamidase; Sulphamidase
Gene Aliases: HSS; MPS3A; SFMD; SGSH
UniProt ID: (Human) P51688
Entrez Gene ID: (Human) 6448
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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