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Product Details
PA5-34438
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid synthetic peptide near the center of human SGSM1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551790
Product Specific Information
A suggested positive control is human cerebellum tissue lysate.
PA5-34438 can be used with blocking peptide PEP-1480.
Target Information
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1, 148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: nurr1-interacting protein; RUN and TBC1 domain containing 2; RUN and TBC1 domain-containing protein 2; Small G protein signaling modulator 1; small G protein signaling modulator 1 protein
Gene Aliases: 2410098H20Rik; AA408781; D5Bwg1524e; E130107M15; KIAA1941; NuIP; RUTBC2; SGSM1
UniProt ID: (Human) Q2NKQ1, (Mouse) Q8BPQ7
Entrez Gene ID: (Human) 129049, (Mouse) 52850, (Rat) 288743
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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