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FIGURE: 1 / 1
Sequence of this protein is as follows: MVQREELLSF MGAEEAAPDP AGVGRGGGVA GPPSGGGGQP QWQKCRLLLR SEGEGGGGSR LEFFVPPKAS RPRLSIPCSS ITDVRTTTAL EMPDRENTFV VKVEGPSEYI METVDAQHVK AWVSDIQECL SPGPCPATSP RPMTLPLAPG TSFLTRENTD SLELSCLNHS ESLPSQDLLL GPSESNDRLS QGAYGGLSDR PSASISPSSA SIAASHFDSM ELLPPELPPR IPIEEGPPAG TVHPLSAPYP PLDTPETATG SFLFQGEPEG GEGDQPLSGY PWFHGMLSRL KAAQLALTGG TGSHGVFLVR QSETRRGEYV LTFNFQGKAK HLRLSLNEEG QCRVQHLWFQ SIFDMLEHFR VHPIPLESGG SSDVVLVSYV PSSQRQQGRE QAGSHAGVCE GDGCHPDASC TLMPFGASDC VTDHLP
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.
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Protein Aliases: DKFZp547G1110; FLJ30542; Pro-rich, PH and SH2 domain-containing signaling mediator; PSM; SH2 B; SH2 domain-containing protein 1B; SH2 domain-containing putative adapter SH2-B; SH2-B signaling protein; SH2B adapter protein 1; SH2B1 protein
Gene Aliases: KIAA1299; PSM; SH2B; SH2B1
UniProt ID: (Human) Q9NRF2
Entrez Gene ID: (Human) 25970
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