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Antibody detects endogenous levels of total SH2B1.
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.
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Protein Aliases: DKFZp547G1110; FceRI gamma-chain-interacting protein SH2-B; FLJ30542; Pro-rich, PH and SH2 domain-containing signaling mediator; PSM; SH2 B; SH2 domain-containing protein 1B; SH2 domain-containing putative adapter SH2-B; SH2-B PH domain containing signaling mediator 1; SH2-B PH domain-containing signaling mediator 1; SH2-B signaling protein; SH2B adapter protein 1; SH2B1 protein
Gene Aliases: AI425885; C530001K22Rik; Irip; KIAA1299; mKIAA1299; PSM; SH2-B; SH2-Bb; SH2B; SH2B1; Sh2bpsm1
UniProt ID: (Human) Q9NRF2, (Rat) Q62985, (Mouse) Q91ZM2
Entrez Gene ID: (Human) 25970, (Rat) 89817, (Mouse) 20399
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