Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: HSEEFTNSL KTKSQYHDLQ APDNQQTKDI WKKVAEKEEL EQGSRPAPTL EEEKIRSLSS SSRNIQQMLA DSINRMKAYA FHQKKESMKK KQDEEINQIE EERTKQICKS WKEDSEWQAS LRKSKAADEK RRSLAKQARE DYKRLSLGAQ KGRGGERLQN PLRVPQKPER PPLPPKPQFL NSGAYPQKPL RNQGVVRTLS SSAQEDIIRW FKEEQLPLRA GYQKTSDTIA PWFHGILTLK KANELLLSTG MPGSFLIRVS ERIKGYALSY LSEDGCKHFL IDASADAYSF LGVDQLQHAT LADLVEYHKE EPITSLGKEL LLYPCGQQDQ LPDYLELFE (1-338 aa encoded by BC014525 )
SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. SH2D4A may play a role in T-cell development and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20967; Protein phosphatase 1 regulatory subunit 38; protein phosphatase 1, regulatory subunit 38; Protein SH(2)A; SH2 domain-containing protein 4A
Gene Aliases: PPP1R38; SH2A; SH2D4A
UniProt ID: (Human) Q9H788
Entrez Gene ID: (Human) 63898
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