Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: LFFKMREEQI RRWKEREAAM ERKESLPVKP RPKKENGKSV HWKLGADKEV WVWVMGEHHL DKPYDVLCNE IIAERARLKA EQEAEEPRKT HSEEFTNSLK TKSQYHDLQA PDNQQTKDIW KKVA
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 73%.
SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. SH2D4A may play a role in T-cell development and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20967; Protein phosphatase 1 regulatory subunit 38; protein phosphatase 1, regulatory subunit 38; Protein SH(2)A; SH2 domain-containing protein 4A
Gene Aliases: PPP1R38; SH2A; SH2D4A
UniProt ID: (Human) Q9H788
Entrez Gene ID: (Human) 63898
Molecular Function:
defense/immunity protein
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