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Invitrogen
SH3BP1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
SH3BP1 Antibody (PA5-81891)
Relative expression in different tissues in IHC: Detection of differential expression levels of SH3BP1 demonstrates antibody specificity. Immunohistochemical analysis of SH3BP1 using anti-SH3BP1 Polyclonal Antibody (Product #PA5-81891), shows significant staining of SH3BP1 in spleen and shows minimal or weak staining in kidney tissues. The relative expression levels of SH3BP1 within each tissue is shown us... View More
Product Details
PA5-81891
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SH3BP1. Recombinant protein control fragment (Product #RP-91341).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789052
Product Specific Information
Immunogen sequence: ENLSNLRYLM KFLARLAEEQ EVNKMTPSNI AIVLGPNLLW PPEKEGDQAQ LDAASVSSIQ VVGVVEALIQ SADTLFPGDI NFNVSGLFSA VTLQDTVSDR LASEELPSTA VPTPATTPAP APAPAPAPAP ALASAATKER TESEVPP
Target Information
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3BP-1; OTTHUMP00000028981; SH3 domain-binding protein 1; SH3-domain binding protein 1
Gene Aliases: ARHGAP43; SH3BP1
UniProt ID: (Human) Q9Y3L3
Entrez Gene ID: (Human) 23616
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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