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The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: EEN; EEN fusion partner of MLL; endophilin A2; endophilin II; Endophilin-2; Endophilin-A2; extra 11-19 leukemia fusion; Extra eleven-nineteen leukemia fusion gene protein; MGC111371; SH3 domain containing GRB2 like 1; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1; SH3-containing Grb-2-like 1 protein; SH3-domain GRB2-like 1; SH3p8
Gene Aliases: C77078; CNSA1; EEN; SH3D2B; SH3GL1; SH3P8
UniProt ID: (Human) Q99961, (Mouse) Q62419, (Rat) O35964
Entrez Gene ID: (Human) 6455, (Mouse) 20405, (Rat) 81922
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