Proteintech

SH3GL2 Polyclonal Antibody

SH3GL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 6

SH3GL2 Antibody (12435-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 12435-1-AP ( SH3GL2 antibody) at dilution of 1:100 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

SH3GL2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12435-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SH3GL2 Fusion Protein Ag3114 (1-279 aa encoded by BC032825)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSVAGLKKQ FHKATQKVSE KVGGAEGTKL DDDFKEMERK VDVTSRAVME IMTKTIEYLQ PNPASRAKLS MINTMSKIRG QEKGPGYPQA EALLAEAMLK FGRELGDDCN FGPALGEVGE AMRELSEVKD SLDIEVKQNF IDPLQNLHDK DLREIQHHLK KLEGRRLDFD YKKERQGKIP DEELRQALEK FDESKEIAES SMFNLLEMDI EQVSQLSALV QAQLEYHKQA VQILQQVTVR LEERIRQASS QPRREYQPKP RMSLEFPTGD STQPNGGLSH (1-279 aa encoded by BC032825)

Target Information

Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma.

Investigative ophthalmology & visual science

Chen S,Chen X,Zhang P,Chen S,Wang X,Luo Q,Cui Z,Huang Y,Wan L,Hou X,Yao H,Liu X,He A,Jiang Z,Qiu J,Li Y,Yu K,Zhuang J

Mon Oct 03 00:00:00 EDT 2022

Loss of Sh3gl2/endophilin A1 is a common event in urothelial carcinoma that promotes malignant behavior.

Neoplasia (New York, N.Y.)

Majumdar S,Gong EM,Di Vizio D,Dreyfuss J,Degraff DJ,Hager MH,Park PJ,Bellmunt J,Matusik RJ,Rosenberg JE,Adam RM

Mon Jul 01 00:00:00 EDT 2013

Loss of Sh3gl2/endophilin A1 is a common event in urothelial carcinoma that promotes malignant behavior.

Neoplasia (New York, N.Y.)

Majumdar S,Gong EM,Di Vizio D,Dreyfuss J,Degraff DJ,Hager MH,Park PJ,Bellmunt J,Matusik RJ,Rosenberg JE,Adam RM

Mon Jul 01 00:00:00 EDT 2013

Loss of Sh3gl2/endophilin A1 is a common event in urothelial carcinoma that promotes malignant behavior.

Neoplasia (New York, N.Y.)

Majumdar S,Gong EM,Di Vizio D,Dreyfuss J,Degraff DJ,Hager MH,Park PJ,Bellmunt J,Matusik RJ,Rosenberg JE,Adam RM

Mon Jul 01 00:00:00 EDT 2013

Loss of Sh3gl2/endophilin A1 is a common event in urothelial carcinoma that promotes malignant behavior.

Neoplasia (New York, N.Y.)

Majumdar S,Gong EM,Di Vizio D,Dreyfuss J,Degraff DJ,Hager MH,Park PJ,Bellmunt J,Matusik RJ,Rosenberg JE,Adam RM

Mon Jul 01 00:00:00 EDT 2013

Bioinformatics

Protein Aliases: bA335L15.1; bA335L15.1 (SH3-domain GRB2-like 2); EEN-B1; endophilin; endophilin A1; Endophilin A1 BAR domain; endophilin I; Endophilin-1; Endophilin-A1; FLJ20276; FLJ25015; SH3 domain containing GRB2 like 2; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3-domain GRB2-like 2; SH3p4

View more View less

Gene Aliases: 9530001L19Rik; AI120490; AW555077; B930049H17Rik; CNSA2; EEN-B1; Een1; SH3D2A; SH3GL2; SH3P4; SH3PA

View more View less

UniProt ID: (Human) Q99962, (Mouse) Q62420, (Rat) O35179

View more View less

Entrez Gene ID: (Human) 6456, (Mouse) 20404, (Rat) 116743

View more View less

Function(s)

protein binding lipid binding identical protein binding

Process(es)

regulation of receptor internalization endocytosis synaptic vesicle endocytosis microtubule-based movement signal transduction central nervous system development antigen processing and presentation of exogenous peptide antigen via MHC class II negative regulation of epidermal growth factor receptor signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

SH3GL2 Polyclonal Antibody

SH3GL2 Antibody (12435-1-AP) in IHC (P)

Product Details

12435-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!