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Product Details
H00006456-M06
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2G6
Immunogen
SH3GL2 (NP_003017, 64 a.a. approximately 124 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: SRAKLSMINT MSKIRGQEKG PGYPQAEALL AEAMLKFGRE LGDDCNFGPA LGEVGEAMRE L
Target Information
Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bA335L15.1; bA335L15.1 (SH3-domain GRB2-like 2); EEN-B1; endophilin; Endophilin A1 BAR domain; Endophilin-1; Endophilin-A1; FLJ20276; FLJ25015; SH3 domain containing GRB2 like 2; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3-domain GRB2-like 2; SH3p4
Gene Aliases: CNSA2; EEN-B1; SH3D2A; SH3GL2; SH3P4
UniProt ID: (Human) Q99962, (Rat) O35179
Entrez Gene ID: (Human) 6456, (Rat) 116743
regulation of receptor internalization
synaptic vesicle endocytosis
microtubule-based movement
signal transduction
central nervous system development
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of epidermal growth factor receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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