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SH3KBP1 Antibody (PA5-96007) in WB
Western blot analysis of SH3KBP1 in extracts of THP-1 cells. Samples were incubated with SH3KBP1 Polyclonal antibody (Product # PA5-96007) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-96007
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 136-271 of human SH3KBP1 (NP_1140981)
Conjugate
Form
Liquid
Concentration
2.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807809
Product Specific Information
Immunogen sequence: WEGVLNGKTG MFPSNFIKEL SGESDELGIS QDEQLSKSSL RETTGSESDG GDSSSTKSEG ANGTVATAAI QPKKVKGVGF GDIFKDKPIK LRPRSIEVEN DFLPVEKTIG KKLPATTATP DSSKTEMDSR TKSKDY; Positive Samples: THP-1; Cellular Location: Cell junction, Cytoplasm, Cytoplasmic vesicle membrane, Peripheral membrane protein, cytoskeleton, focal adhesion, synapse, synaptosome
Target Information
This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-Cbl-interacting protein; Cbl-interacting protein of 85 kDa; CD2-binding protein 3; CD2BP3; HSB-1; Human Src family kinase-binding protein 1; migration-inducing gene 18; Regulator of ubiquitous kinase; Ruk; SH3 domain-containing kinase-binding protein 1; SH3-containing, expressed in tumorigenic astrocytes; SH3-domain kinase binding protein 1; Src family kinase-binding protein 1; src-related kinase binding protein-1
Gene Aliases: 1200007H22Rik; 1700125L08Rik; 5830464D22Rik; AI447724; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IN85; MIG18; Ruk; Seta; SH3KBP1
UniProt ID: (Human) Q96B97, (Mouse) Q8R550
Entrez Gene ID: (Human) 30011, (Mouse) 58194
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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