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SHBG Antibody (PA5-96682) in IHC (P)
Immunohistochemistry analysis of SHBG in paraffin-embedded human liver cancer. Samples were incubated with SHBG Polyclonal antibody (Product # PA5-96682) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-96682
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-170 of human SHBG (NP_0010312)
Conjugate
Form
Liquid
Concentration
0.73 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808484
Product Specific Information
Immunogen sequence: LRPVLPTQSA HDPPAVHLSN GPGQEPIAVM TFDLTKITKT SSSFEVRTWD PEGVIFYGDT NPKDDWFMLG LRDGRPEIQL HNHWAQLTVG AGPRLDDGRW HQVEVKMEGD SVLLEVDGEE VLRLRQVSGP LTSKRHPIMR I; Positive Samples: A-549, Human placenta, Mouse testis
Target Information
SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABP; androgen binding protein; Androgen binding protein (ABP); SBP; Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene); Sex hormone-binding globulin; Sex hormone-binding globulin (SHBG); Sex steroid binding protein (SBP); Sex steroid-binding protein; SHBG; TeBG; Testis-specific androgen-binding protein; Testosterone binding beta globulin; testosterone-binding beta-globulin; Testosterone-estradiol-binding globulin; Testosterone-Estradiol-Binding Globulin (TEBG); Testosterone-estrogen-binding globulin
Gene Aliases: ABP; Abpa; SBP; SHBG; TEBG
UniProt ID: (Human) P04278, (Rat) P08689, (Mouse) P97497
Entrez Gene ID: (Human) 6462, (Rat) 24775, (Mouse) 20415
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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