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Product Details
PA5-62449
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SHROOM2. Recombinant protein control fragment (Product #RP-95447).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647289
Product Specific Information
Immunogen sequence: PPLLIQDEDS TRIERVMDNN TTVKMVPIKI VHSESQPEKE SRQSLACPAE PPALPHGLEK DQIKTLSTSE QFYS
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 89%.
Target Information
The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apical-like protein; APX homolog of Xenopus; Protein APXL; Protein Shroom2
Gene Aliases: APXL; HSAPXL; SHROOM2
UniProt ID: (Human) Q13796
Entrez Gene ID: (Human) 357
cell morphogenesis
lens morphogenesis in camera-type eye
brain development
eye pigment granule organization
cell migration
establishment of melanosome localization
melanosome organization
sodium ion transmembrane transport
camera-type eye development
cellular pigment accumulation
ear development
apical protein localization
camera-type eye morphogenesis
actin filament bundle assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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