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In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human (rh) Siglec-5 is observed and less than 1% cross-reactivity with rhSiglec-2, rhSiglec-3, rhSiglec-7, rhSiglec-9, and recombinant mouse Siglec-F is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: sialic acid binding Ig-like lectin 10 Ig-like lectin 7; Sialic acid-binding Ig-like lectin 10; Siglec; Siglec-10; siglec-like gene 2; Siglec-like protein 2
Gene Aliases: PRO940; SIGLEC-10; SIGLEC10; SLG2; UNQ477/PRO940
UniProt ID: (Human) Q96LC7
Entrez Gene ID: (Human) 89790
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