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SIGLEC9 (Sialic acid-binding Ig-like lectin 9) is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It preferentially binds to alpha2, 3-or alpha2, 6-linked sialic acid. The sialic acid recognition site may be mased by cis interactions with sialic acids on the same cell surface.
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Protein Aliases: CD327; CD33 antigen-like 1; CDw327; OB-BP1; Obesity-binding protein 1; sialic acid binding Ig-like lectin 6; Sialic acid-binding Ig-like lectin 6; Siglec; Siglec-6
Gene Aliases: CD327; CD33L; CD33L1; CD33L2; CDW327; OBBP1; SIGLEC6
UniProt ID: (Human) O43699
Entrez Gene ID: (Human) 946
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