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Product Details
MA5-21444
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2C11
Immunogen
SIN3B (NP_056075.1, 1063 a.a. ~ 1160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.2-1.0 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610080
Product Specific Information
Peptide Sequence: HKMVFIVNSE DYMYRRGTLC RAKQVQPLVL LRHHQHFEEW HSRWLEDNVT VEAASLVQDW LMGEEDEDMV PCKTLCETVH VHGLPVTRYR VQYSRRPA
Target Information
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Histone deacetylase complex subunit Sin3b; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b
Gene Aliases: KIAA0700; SIN3B
UniProt ID: (Human) O75182
Entrez Gene ID: (Human) 23309
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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