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SIPA1L2 Antibody (A304-677A) in IP
Detection of human SIPA1L2 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SIPA1L2 antibody A304-677A (lot A304-677A-1) used for IP at 6 µg per reaction. SIPA1L2 was also immunoprecipitated by rabbit anti-SIPA1L2 antibody BL17930. For blotting immunoprecipitated SIPA1L2, A304-677A was used at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time... View More
Product Details
A304-677A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1250 to 1300 of Human Signal-Induced Proliferation-Associated 1 Like 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: signal-induced proliferation-associated 1 like 2; Signal-induced proliferation-associated 1-like protein 2; SIPA1-like protein 2; SPA-1-like 2
Gene Aliases: KIAA1389; SIPA1L2; SPAL2
UniProt ID: (Human) Q9P2F8
Entrez Gene ID: (Human) 57568
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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