Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: MPKRSCPFAD VAPLQLKVRV SQRELSRGVC AERYSQEVFD PSGVASIACS SCVRAVDGKA VCGQCERALC GQCVRTCWGC GSVACTLCGL VDCSDMYEKV LCTSCAMFET; Positive Samples: MCF7, SW620; Cellular Location: Cytoplasm, Nucleus
Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis regulatory protein Siva; CD27-binding (Siva) protein; CD27-binding protein; CD27BP; SIVA1, apoptosis-inducing factor
Gene Aliases: CD27BP; SIVA; Siva-1; Siva-2; SIVA1
UniProt ID: (Human) O15304
Entrez Gene ID: (Human) 10572
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