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Invitrogen
SIX2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 3
SIX2 Antibody (PA5-84322) in WB
Western blot was performed using SIX2 Polyclonal Antibody (Product # PA5-84322) and a ~35 kDa band corresponding to SIX2 was observed across cell lines and tissues. Nuclear enriched extracts (30 µg lysate) of RD (Lane 1), IMR-32 (Lane 2), HeLa (Lane 3), HEK-293 (Lane 4), Hep G2 (Lane 5), BeWo (Lane 6), A-431 (Lane 7), A549 (Lane 8), Mouse Skeletal Muscle (Lane 9), Rat Skeletal Muscle (Lane 10), Mouse Spleen (Lane 11) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX), 12 well. Resolved proteins were then tr... View More
Product Details
PA5-84322
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SIX2. Recombinant protein control fragment (Product #RP-106741).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791474
Product Specific Information
Immunogen sequence: ADPLQHHHGL QDSILNPMSA NLVDLGS
Target Information
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Homeobox protein SIX2; Sine oculis homeobox homolog 2
Gene Aliases: SIX2
UniProt ID: (Human) Q9NPC8
Entrez Gene ID: (Human) 10736
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein complex binding
homeodomain transcription factor
kidney development
chondrocyte differentiation
mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription from RNA polymerase II promoter
protein import into nucleus
mesodermal cell fate specification
cell proliferation
anatomical structure morphogenesis
anterior/posterior axis specification
cell migration
regulation of ossification
regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
nephron development
nephron morphogenesis
mesenchymal stem cell maintenance involved in nephron morphogenesis
mesenchymal cell differentiation involved in kidney development
regulation of branching involved in ureteric bud morphogenesis
mesenchymal stem cell proliferation
positive regulation of chondrocyte proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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