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Product Details
CL594-66347
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1F9G11
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSMLPTFGFT QEQVACVCEV LQQGGNIERL GRFLWSLPAC EHLHKNESVL KAKAVVAFHR GNFRELYKIL ESHQFSPHNH AKLQQLWLKA HYIEAEKLRG RPLGAVGKYR VRRKFPLPRS IWDGEETSYC FKEKSRSVLR EWYAHNPYPS PREKRELTEA TGLTTTQVSN WFKNRRQRDR AAEAKERENN ENSNSNSHNP LNGSGKSVLG SSEDEKTPSG TPDHSSSSPA LLLSPPPPGL PSLHSLGHPP GPSAVPVPVP GGGGADPLQH HHGLQDSILN PMSANLVDLG S
Target Information
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Homeobox protein SIX2; Sine oculis homeobox homolog 2; sine oculis-related homeobox 2 homolog
Gene Aliases: SIX2
UniProt ID: (Human) Q9NPC8, (Mouse) Q62232
Entrez Gene ID: (Pig) 100525814, (Human) 10736, (Dog) 481357, (Mouse) 20472, (Rat) 366542
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein complex binding
DNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
kidney development
chondrocyte differentiation
mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription from RNA polymerase II promoter
protein import into nucleus
mesodermal cell fate specification
cell proliferation
anatomical structure morphogenesis
anterior/posterior axis specification
cell migration
regulation of ossification
regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
nephron development
nephron morphogenesis
mesenchymal stem cell maintenance involved in nephron morphogenesis
mesenchymal cell differentiation involved in kidney development
regulation of branching involved in ureteric bud morphogenesis
mesenchymal stem cell proliferation
positive regulation of chondrocyte proliferation
metanephros development
regulation of transcription, DNA-templated
multicellular organism development
embryonic skeletal system morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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