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Product Details
H00006499-M05A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1E5
Immunogen
SKIV2L (NP_008860, 1125 a.a. approximately 1233 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: DQLPNTLKQG IERVRAVAKR IGEVQVACGL NQTVEEFVGE LNFGLVEVVY EWARGMPFSE LAGLSGTPEG LVVRCIQRLA EMCRSLRGAA RLVGEPVLGA KMETAATLL
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Helicase-like protein; HLP; Ski2; SKI2 homolog, superkiller viralicidic activity 2-like; Superkiller complex protein 2; superkiller viralicidic activity 2-like
Gene Aliases: 170A; DDX13; HLP; SKI2; SKI2W; SKIC2; SKIV2; SKIV2L; SKIV2L1; THES2; W
UniProt ID: (Human) Q15477
Entrez Gene ID: (Human) 6499
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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