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Product Details
CF505078
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1D8
Immunogen
Full length human recombinant protein of human SLA2 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MARS; Modulator of antigen receptor signaling; SLAP-2; Src-like adapter protein 2; Src-like adapter protein-2; Src-like-adapter 2; Src-like-adaptor 2
Gene Aliases: C20orf156; MARS; SLA2; SLAP-2; SLAP2
UniProt ID: (Human) Q9H6Q3
Entrez Gene ID: (Human) 84174
negative regulation of transcription from RNA polymerase II promoter
positive regulation of signal transduction
B cell mediated immunity
intracellular receptor signaling pathway
T cell activation
regulation of immune response
negative regulation of calcium-mediated signaling
antigen receptor-mediated signaling pathway
negative regulation of B cell activation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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