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SLAIN2 Antibody (A303-647A) in IP
Detection of human SLAIN2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SLAIN2 antibody A303-647A used for IP at 6 µg/mg lysate. SLAIN2 was also immunoprecipitated by rabbit anti-SLAIN2 antibody A303-646A, which recognizes an upstream epitope. For blotting immunoprecipitated SLAIN2, A303-647A was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Product Details
A303-647A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 531 and 581 of Human SLAIN Motif Family, Member 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ21611; SLAIN motif family, member 2; SLAIN motif-containing protein 2
Gene Aliases: KIAA1458; SLAIN2
UniProt ID: (Human) Q9P270
Entrez Gene ID: (Human) 57606
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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