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Positive Control: HepG2, HepG2 cytoplasm and membrane fraction extract
Predicted Reactivity: Mouse (95%), Rat (93%), Pig (90%), Chimpanzee (100%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hairpin binding protein, histone; histone binding protein; Histone RNA hairpin-binding protein; histone stem-loop binding protein; Histone stem-loop-binding protein; stem-loop (histone) binding protein
Gene Aliases: HBP; SLBP
UniProt ID: (Human) Q14493
Entrez Gene ID: (Human) 7884
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