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Invitrogen
SLC10A2 Polyclonal Antibody
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SLC10A2 Antibody (PA5-18990) in IHC (P)
Immunohistochemistry analysis of SLC10A2 Polyclonal Antibody (Product # PA5-18990) was performed on a pig ileum fixed in 10% formalin for 24 hours. To expose target proteins, antigen retrieval was performed by heating tissues in a pressure cooker for 10 minutes in 10mM sodium citrate buffer (pH 6.0). Following antigen retrieval, endogenous peroxidases were blocked with 3% hydrogen peroxide for 10 min at roo... View More
Product Details
PA5-18990
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Dog
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (DETNKGFQPDEK) corresponding to the C-terminus amino acids of Slc10a2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_10981375
Product Specific Information
This antibody is predicted to react with rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); mutations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Apical sodium-dependent bile acid transporter; ASBT; IBAT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2
Gene Aliases: ASBT; ISBT; Ntcp2; Slc10a2
UniProt ID: (Mouse) Q925U7
Entrez Gene ID: (Mouse) 20494
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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