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Product Details
OSS00359W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mouse SLC11A2 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SLC11A2.
Target Information
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dct-1; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; microcytic anemia, viable anaemia; Natural resistance-associated macrophage protein 2; NRAMP 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2; Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2)
Gene Aliases: DCT1; DMT1; mk; Nramp2; Slc11a2; van
UniProt ID: (Mouse) P49282, (Rat) O54902
Entrez Gene ID: (Mouse) 18174, (Rat) 25715
transporter activity
copper ion transmembrane transporter activity
iron ion transmembrane transporter activity
manganese ion transmembrane transporter activity
iron ion binding
copper ion binding
zinc ion binding
hydrogen ion transmembrane transporter activity
cadmium ion transmembrane transporter activity
cobalt ion transmembrane transporter activity
ferrous iron transmembrane transporter activity
lead ion transmembrane transporter activity
nickel cation transmembrane transporter activity
vanadium ion transmembrane transporter activity
solute:proton symporter activity
ferrous iron uptake transmembrane transporter activity
nickel cation binding
inorganic cation transmembrane transporter activity
manganese ion binding
cadmium ion binding
transition metal ion transmembrane transporter activity
cobalt ion binding
zinc ion transmembrane transporter activity
calcium ion transmembrane transporter activity
chromium ion transmembrane transporter activity
secondary carrier transporter
transition metal ion transport
porphyrin-containing compound metabolic process
porphyrin-containing compound biosynthetic process
heme biosynthetic process
transport
ion transport
cobalt ion transport
copper ion transport
iron ion transport
manganese ion transport
cellular copper ion homeostasis
activation of cysteine-type endopeptidase activity involved in apoptotic process
learning or memory
response to manganese ion
nickel cation transport
vanadium ion transport
ferrous iron transport
lead ion transport
proton transport
cellular response to oxidative stress
iron ion transmembrane transport
copper ion transmembrane transport
nickel cation transmembrane transport
dendrite morphogenesis
erythrocyte development
iron ion homeostasis
multicellular organismal iron ion homeostasis
cadmium ion transmembrane transport
ferrous iron import
manganese ion transmembrane transport
zinc II ion transmembrane transport
cation transmembrane transport
hydrogen ion transmembrane transport
copper ion import into cell
ferrous iron transmembrane transport
response to hypoxia
detection of oxygen
response to iron ion
response to lead ion
response to cadmium ion
cellular response to iron ion
cellular response to tumor necrosis factor
cellular response to hypoxia
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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