Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.
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Protein Aliases: DKFZp547C109; hMRS3/4; Mitochondrial iron transporter 2; mitochondrial RNA splicing protein 3/4; Mitochondrial RNA-splicing protein 3/4 homolog; mitoferrin 2; Mitoferrin-2; MRS3/4; putative mitochondrial solute carrier; solute carrier family 25 (mitochondrial iron transporter), member 28; Solute carrier family 25 member 28; solute carrier family 25, member 28
Gene Aliases: MFRN2; MRS3/4; MRS4L; NPD016; SLC25A28
UniProt ID: (Human) Q96A46
Entrez Gene ID: (Human) 81894
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