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Product Details
27759-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC26A2 Fusion Protein Ag26521 (1-112 aa encoded by BC059390)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSSESKEQH NVSPRDSAEG NDSYPSGIHL ELQRESSTDF KQFETNDQCR PYHRILIERQ EKSDTNFKEF VIKKLQKNCQ CSPAKAKNMI LGFLPVLQWL PKYDLKKNIL GDV (1-112 aa encoded by BC059390)
Target Information
The SLC26 family is comprised of sulfate/anion transporters that are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns. Members of the SLC26 family can mediate the electroneutral exchange of Cl- for HCO3- across the plasma membrane of mammalian cells. SLC26A2 (solute carrier family 26, member 2), also known as DTD, EDM4, DTDST, MST153, D5S1708 or MSTP157, is a 739 amino acid diastrophic dysplasia sulfate transporter belonging to the SLC26A/SulP transporter family. Ubiquitously expressed, SLC26A2 may play a role in endochondral bone formation. SLC26A2 is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias and is critical for sulfation of proteoglycans and matrix organization in cartilage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Diastrophic dysplasia protein; Diastrophic dysplasia protein homolog; solute carrier family 26 (anion exchanger), member 2; solute carrier family 26 (sulfate transporter), member 2; Solute carrier family 26 member 2; ST-OB; sulfate anion transporter 1; Sulfate transporter
Gene Aliases: D5S1708; DTD; DTDST; EDM4; MST153; MSTP157; SLC26A2; ST-OB
UniProt ID: (Human) P50443, (Mouse) Q62273, (Rat) O70531
Entrez Gene ID: (Human) 1836, (Mouse) 13521, (Rat) 117267
ossification
ion transport
sulfate transport
bicarbonate transport
oxalate transport
regulation of membrane potential
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
regulation of intracellular pH
sulfate transmembrane transport
chloride transmembrane transport
transport
transmembrane transport
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