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Product Details
SLC26A3-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids within region 520-570 on human SCL26A3 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer with 20% glycerol, 0.5% BSA
Contains
0.01% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Quantity: 100 µg IgG per vial
Target Information
SLC26A3 is a chloride/bicarbonate exchanger that is involved in absorption inside the colon. SLC26A3 helps mediate electrolyte and fluid absorption. The protein encoded by the SLC26A3 gene is a transmembrane glycoprotein that functions as a sulfate transporter, and it is localized to the mucosa. The chloride ions transported by SLC26A3 cross the cell membrane in exchange for biocarbonate ions. SLC26A3 is localized in the mucosa of the lower intestinal tract, specifically the apical membrane of the columnar epithelium and in some goblet cells. Diseases associated with SLC26A3 protein dysfunction include congenital chloride diarrhea and congenital secretory chloride diarrhea 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chloride anion exchanger; Down-regulated in adenoma; down-regulated in adenoma protein; Protein DRA; solute carrier family 26 (anion exchanger), member 3; Solute carrier family 26 member 3; solute carrier family 26, member 3
Gene Aliases: 9030623B18Rik; 9130013M11Rik; AV376035; CLD; DRA; SLC26A3
UniProt ID: (Human) P40879, (Mouse) Q9WVC8, (Rat) Q924C9
Entrez Gene ID: (Human) 1811, (Mouse) 13487, (Rat) 114629
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
transporter activity
chloride channel activity
inorganic anion exchanger activity
protein binding
secondary active sulfate transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
sulfate transmembrane transporter activity
anion:anion antiporter activity
oxalate transmembrane transporter activity
antiporter activity
transporter
regulation of transcription, DNA-templated
ion transport
anion transport
excretion
bicarbonate transport
oxalate transport
regulation of membrane potential
sperm capacitation
regulation of intracellular pH
intracellular pH elevation
membrane hyperpolarization
cellular response to cAMP
sulfate transmembrane transport
chloride transmembrane transport
transport
chloride transport
sulfate transport
transmembrane transport
anion transmembrane transport
Performance Guarantee
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