Invitrogen

SLC27A1 Polyclonal Antibody

View all (10) SLC27A1 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-110387

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 510-646 of human SLC27A1 (NP_9409821)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.88 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855798

Product Specific Information

Immunogen sequence: DTFRWRGENV STTEVEGVLS RLLGQTDVAV YGVAVPGVEG KAGMAAVADP HSLLDPNAIY QELQKVLAPY ARPIFLRLLP QVDTTGTFKI QKTRLQREGF DPRQTSDRLF FLDLKQGHYL PLNEAVYTRI CSGAFAL

Target Information

SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ACSVL5FATP-1; Arachidonate--CoA ligase; EC 6.2.1; FATP-1; Fatty acid transport protein; Fatty acid transport protein 1; FLJ00336; Long-chain fatty acid transport protein 1; Long-chain-fatty-acid--CoA ligase; MGC71751; solute carrier family 27 (fatty acid transporter), member 1; Solute carrier family 27 member 1; solute carrier family 27, member 1; Very long-chain acyl-CoA synthetase; Vlc27a1

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Gene Aliases: ACSVL5; FATP; FATP-1; FATP1; SLC27A1

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UniProt ID: (Human) Q6PCB7, (Mouse) Q60714

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Entrez Gene ID: (Human) 376497, (Rat) 94172, (Mouse) 26457

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Function(s)
nucleotide binding long-chain fatty acid-CoA ligase activity fatty acid transporter activity very long-chain fatty acid-CoA ligase activity protein homodimerization activity protein binding catalytic activity acyl-CoA ligase activity succinate-CoA ligase activity 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity fatty acid ligase activity ligase activity 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity benzoyl acetate-CoA ligase activity 2,4-dichlorobenzoate-CoA ligase activity pivalate-CoA ligase activity cyclopropanecarboxylate-CoA ligase activity adipate-CoA ligase activity citronellyl-CoA ligase activity mentha-1,3-dione-CoA ligase activity thiophene-2-carboxylate-CoA ligase activity 2,4,4-trimethylpentanoate-CoA ligase activity cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity branched-chain acyl-CoA synthetase (ADP-forming) activity aryl-CoA synthetase (ADP-forming) activity 3-hydroxypropionyl-CoA synthetase activity perillic acid:CoA ligase (ADP-forming) activity perillic acid:CoA ligase (AMP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity pristanate-CoA ligase activity malonyl-CoA synthetase activity transporter secondary carrier transporter
Process(es)
medium-chain fatty acid transport long-chain fatty acid metabolic process phosphatidylethanolamine biosynthetic process phosphatidic acid biosynthetic process phosphatidylglycerol biosynthetic process phosphatidylcholine biosynthetic process phosphatidylserine biosynthetic process phosphatidylinositol biosynthetic process response to cold long-chain fatty acid transport positive regulation of heat generation cardiolipin biosynthetic process response to insulin adiponectin-activated signaling pathway negative regulation of phospholipid biosynthetic process positive regulation of protein serine/threonine kinase activity biological_process fatty acid transport lipid metabolic process fatty acid metabolic process transport lipid transport metabolic process
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